Chronic Fatigue Syndrome Blog Posts
In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation.

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is accompanied by activation of immuno-inflammatory pathways, increased bacterial translocation and autoimmune responses to serotonin (5-HT). Inflammation is known to damage 5-HT neurons whi...
by PolygenicBlog on May 15, 2013
Detection of mycotoxins in patients with chronic fatigue syndrome.

Over the past 20 years, exposure to mycotoxin producing mold has been recognized as a significant health risk. Scientific literature has demonstrated mycotoxins as possible causes of human disease in water-damaged buildings (WDB). This study was cond...
by PolygenicBlog on Apr 13, 2013
Lipid and protein oxidation in female patients with chronic fatigue syndrome.

Chronic fatigue syndrome (CFS) is a widely recognized problem, characterized by prolonged, debilitating fatigue and a characteristic group of accompanying symptoms, that occurs four times more frequently in women than in men. The aim of the study was...
by PolygenicBlog on Nov 28, 2012
Chronic fatigue syndrome: System under stress

"ScienceDaily (Nov. 14, 2012) — Australian researchers have discovered for the first time that reduced heart rate variability -- or changes in heart beat timing -- best predicts cognitive disturbances, such as concentration difficulties commonly re...
by PolygenicBlog on Nov 16, 2012
Discovery could lead to faster diagnosis for some chronic fatigue syndrome cases

In a pilot study of six patients, scientists detected specific antibodies linked to latent Epstein-Barr virus reactivation in blood samples from people who had experienced classic CFS symptoms and responded to antiviral treatment. Control blood sampl...
by PolygenicBlog on Nov 15, 2012
Fibromyalgia and the brain: New clues reveal how pain and therapies are processed

ScienceDaily (Nov. 10, 2012) — According to research presented this week at the American College of Rheumatology Annual Meeting in Washington, D.C., pain experienced by people with fibromyalgia may be caused by a problem with the way pain stim...
by PolygenicBlog on Nov 12, 2012
Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers.

Valganciclovir has been reported to improve physical and cognitive symptoms in patients with chronic fatigue syndrome (CFS) with elevated human herpesvirus 6 (HHV-6) and Epstein-Barr virus (EBV) IgG antibody titers. This study investigated whether an...
by PolygenicBlog on Oct 20, 2012
Association of active human herpesvirus-6, -7 and parvovirus b19 infection with clinical outcomes in patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Frequency of active human herpesvirus-6, -7 (HHV-6, HHV-7) and parvovirus B19 (B19) infection/coinfection and its association with clinical course of ME/CFS was evaluated. 108 ME/CFS patients and 90 practically healthy persons were enrolled in the st...
by PolygenicBlog on Sep 29, 2012
New study finds chronic fatigue syndrome not linked to XMRV and pMLV viruses

The causes of chronic fatigue syndrome (CFS) have long eluded scientists. In 2009, a paper in the journal Science linked the syndrome—sometimes called myalgic encephalomyelitis (ME)—to infection with a mouse retrovirus called XMRV (xenotropic mur...
by PolygenicBlog on Sep 19, 2012
Association of Active Human Herpesvirus-6, -7 and Parvovirus B19 Infection with Clinical Outcomes in Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Frequency of active human herpesvirus-6, -7 (HHV-6, HHV-7) and parvovirus B19 (B19) infection/coinfection and its association with clinical course of ME/CFS was evaluated. 108 ME/CFS patients and 90 practically healthy persons were enrolled in the...
by PolygenicBlog on Aug 29, 2012
Activation of cell-mediated immunity in depression: association with inflammation, melancholia, clinical staging and the fatigue and somatic symptom cluster of depression.

Depression is characterized by activation of cell-mediated immunity (CMI), including increased neopterin levels, and increased pro-inflammatory cytokines (PICs), such as interleukin-1 (IL-1) and tumor necrosis factor-α (TNFα). These PICs may ind...
by PolygenicBlog on Aug 25, 2012
There’s A Rainbow Somewhere!

She woke up on a lovely Friday morning as the raindrops fell pitter-patter on the window. She covered her ears tightly and thought of the wonderful times when she was a child. The same sound would make her jump out of the bed, look at the clouds and...
by Everyday Gyaan on Aug 17, 2012
Mitochondrial dysfunction and the pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

The objectives of this study are to test the hypothesis that the fatigue and accompanying symptoms of Chronic Myalgic Encephalomyelitis/Fatigue Syndrome are in part due to defects in energy provision at the cellular level, and to understand the pa...
by PolygenicBlog on Aug 5, 2012
Fatigue Before, During and After Antiviral Therapy of Chronic Hepatitis C: Results from the Virahep-C Study.

Fatigue is the most frequent and often debilitating symptom of chronic hepatitis C. It is unclear whether successful therapy of hepatitis C leads to its clinical improvement. In the Virahep-C study, patients with hepatitis C virus (HCV) genotype 1...
by PolygenicBlog on Jul 5, 2012
IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression.

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and depression are considered to be neuro-immune disorders (Maes and Twisk, BMC Medicine 8:35, 2010). There is also evidence that depression and ME/CFS are accompanied by oxidative and ni...
by PolygenicBlog on May 27, 2012
KEGG pathway analysis of the genes implicated in chronic fatigue syndrome

There are relatively few genetic studies on chronic fatigue syndrome /fibromyalgia compared to other disorders, and a systems biology approach is necessarily limited. The main thrust so far seems to be related to neurotransmitter systems,(dopamine/ g...
by PolygenicBlog on May 21, 2012
Treatment of Chronic Fatigue Syndrome as an Immunological Disorder - Autoimmunity Network

At the 2012 International Congress on Autoimmunity, in Granada, Spain, Inge Lindseth, from Oslo, Norway, presented a case series of 63 Chronic Fatigue Syndrome ( CFS/ME ) patients from Canada and Norway, who, in general, are responding well to an...
by PolygenicBlog on May 20, 2012
Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis.

Chronic fatigue / Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an etiologically unexplained disorder characterised by irregularities in various aspects of the immunological function. Presently, it is unknown whether these immunological changes r...
by PolygenicBlog on May 11, 2012
GBE2 Blog Challenge Day Three

Day 03: Something with which you struggleI have chronic fatigue syndrome. I got a case of mono that nearly killed me when I was 17, and ever since then fatigue is what I will deal with every day of my life. The thing that really sucks is...
by The Kate Escape on May 5, 2012
Time for Action – Campaign from Action for M.E
Action for M.E s has launched a new campaign called Time for Action. Action for M.E have started this campaign as people with M.E feel strongly that they have a raw deal from the Government and the NHS over the last 20 years compared with many other...
by Confessions of a single mum on Feb 9, 2012
