Cystic Fibrosis Blog Posts

Three Ways to Run for a Good Cause

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by Education Blog on Jan 15, 2013

New website to unite cystic fibrosis patients and researchers

People with cystic fibrosis (CF) will be able to access the latest research findings about their condition, volunteer for clinical trials and influence the direction of future scientific studies through a new website being launched later this week.&n...
by PolygenicBlog on Jan 9, 2013

Grill’d Brookfield Place, Perth

Since opening earlier this year, Brookfield Place has quickly become something of a food haven in the centre of the CBD.  With a plethora of bars, restaurants and cafes all in one complex it’s a wonder those who work in the city ever want to leave...
by Chompchomp on Dec 13, 2012

Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing

The expression of cystic fibrosis transmembrane conductance regulator (CFTR) in lymphocytes has been reported for nearly two decades; however, its physiological role remains elusive. Here, we report that co-culture of lymphocytes with lung epithelial...
by PolygenicBlog on Nov 7, 2012

Futurity.org – Sea sponge chemical fixes cystic fibrosis defect

A chemical from a marine sponge found in the South Pacific Ocean restores function in a defective protein that causes cystic fibrosis, a fatal genetic disease. pub-5799224524264318...
by PolygenicBlog on Oct 28, 2012

Cystic fibrosis transmembrane conductance regulator knockout mice exhibit aberrant gastrointestinal microbiota.

The composition of the gastrointestinal microbiome is increasingly recognized as a crucial contributor to immune and metabolic homeostasis-deficiencies in which are characteristic of cystic fibrosis (CF) patients. The murine model (CFTR (-/-) , CF),...
by PolygenicBlog on Oct 14, 2012

Airways More Acidic In Cystic Fibrosis Patients, Less Effective At Killing Bacteria

The human airway is a pretty inhospitable place for microbes. There are numerous immune defense mechanisms poised to kill or remove inhaled bacteria before they can cause problems. But cystic fibrosis (CF) disrupts these defenses, leaving patients...
by PolygenicBlog on Aug 19, 2012

Exome sequencing of health condition extremes can reveal susceptibility genes

Comparing the DNA from patients at the best and worst extremes of a health condition can reveal genes for resistance and susceptibility. This approach discovered rare variations in the DCTN4 gene among cystic fibrosis patients most prone to early,...
by PolygenicBlog on Jul 9, 2012

Cystic fibrosis makes airways more acidic, reduces bacterial killing

The human airway is a pretty inhospitable place for microbes. There are numerous immune defense mechanisms poised to kill or remove inhaled bacteria before they can cause problems. But cystic fibrosis (CF) disrupts these defenses, leaving patients...
by PolygenicBlog on Jul 5, 2012

MicrobeWorld - Garlic Constituent Blocks Biofilm Formation, Could Benefit Cystic Fibrosis Patients and Others

Bacterial biofilms are far more resistant than individual bacteria to the armories of antibiotics we have devised to combat them. Now Tim Holm Jakobsen and Michael Givskov of the University of Copenhagen, and their many collaborators have pinpoint...
by PolygenicBlog on May 28, 2012

Cystic fibrosis breakthrough reveals why females fare worse than males

Researchers from the Respiratory Research Division of the Department of Medicine, Royal College of Surgeons in Ireland (RCSI) have published a study which represents a major breakthrough in understanding why females with cystic fibrosis do worse t...
by PolygenicBlog on May 26, 2012

Bacteriophages ϕMR299-2 and ϕNH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells

Given the rise in antibiotic resistance, nonantibiotic therapies are required for the treatment of infection. This is particularly true for the treatment of Pseudomonas infection in patients with cystic fibrosis. We have iden...
by PolygenicBlog on May 2, 2012

Why one bacterial infection is so deadly in cystic fibrosis patients: Pathogen interferes with cells whose job is to fight infection

The Ohio State University researchers have determined that B. cenocepacia bacteria interfere with an important survival process in cells whose job is to fight infection. This phenomenon is even stronger in Cystic fibrosis  patients, so the in...
by PolygenicBlog on Apr 23, 2012

Self Diagnosis Of Medical Condition Bronchiectasis

Self Diagnosis Of Medical Condition Bronchiectasis Bronchiectasis is a lung condition where the bronchi (airways leading to the lungs) are chronically dilated (expanded). This medical condition cannot be reversed but there are specific treatments aim...
by Road To Good Healthy Life on Apr 22, 2012

Bacteriophages and diffusion of genes encoding antimicrobial resistance in cystic fibrosis sputum microbiota.

The cystic fibrosis (CF) airway is now considered the site of a complex microbiota, where cross-talking between microbes and lateral gene transfer are believed to contribute to the adaptation of bacteria to this specific environment and to the emerge...
by PolygenicBlog on Mar 22, 2012

Bacteriophages as vehicles of the resistome in cystic fibrosis.

Environmental microbial communities and human microbiota represent a huge reservoir of mobilizable genes, the 'mobilome', including a pool of genes encoding antimicrobial resistance, the 'resistome'. Whole-genome sequencing of bacterial genomes from...
by PolygenicBlog on Mar 22, 2012

Cystic fibrosis gene therapy program gets green light with public funding

A groundbreaking gene therapy trial for cystic fibrosis will begin in March, thanks to a new grant from a government funding body. One hundred and thirty adults and children with CF will take part in the largest trial of its type yet, coordinated...
by PolygenicBlog on Mar 16, 2012

Local Events for the Foodie in You: Week of January 30th!

Pin it The time has come! Well, almost. We are moving in 1 day!  One day, I’m nervous, stressed out, and seriously excited. I get a full, new kitchen, a new neighborhood, a lot of new turf to cover & restaurants to try out. Unfortunately f...
by New York City Eats on Jan 30, 2012

Inhaled Dry Powder for Cystic Fibrosis | Medical News and Health Information

pub-5799224524264318...
by PolygenicBlog on Dec 21, 2011

Ivacaftor, New Drug for Lung Disease Cystic Fibrosis

The researchers found new hope to help cure lung disease patients cystic fibrosis with drug discovery ivacaftor. As quoted by VOA News from the New England Journal of Medicine, the drug is believed to be able to balance between salt and water content...
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