Hhv-6 Blog Posts

Response to valganciclovir in chronic fatigue syndrome patients with human herpesvirus 6 and Epstein-Barr virus IgG antibody titers.

Valganciclovir has been reported to improve physical and cognitive symptoms in patients with chronic fatigue syndrome (CFS) with elevated human herpesvirus 6 (HHV-6) and Epstein-Barr virus (EBV) IgG antibody titers. This study investigated whether an...
by PolygenicBlog on Oct 20, 2012

Imbalanced Oxidative Stress Causes Chlamydial Persistence during Non-Productive Human Herpes Virus Co-Infection.

Both human herpes viruses and Chlamydia are highly prevalent in the human population and are detected together in different human disorders. Here, we demonstrate that co-infection with human herpes virus 6 (HHV6) interferes with the developmental cyc...
by PolygenicBlog on Oct 19, 2012

Association of active human herpesvirus-6, -7 and parvovirus b19 infection with clinical outcomes in patients with myalgic encephalomyelitis/chronic fatigue syndrome.

Frequency of active human herpesvirus-6, -7 (HHV-6, HHV-7) and parvovirus B19 (B19) infection/coinfection and its association with clinical course of ME/CFS was evaluated. 108 ME/CFS patients and 90 practically healthy persons were enrolled in the st...
by PolygenicBlog on Sep 29, 2012

Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis.

Some of the strongest associations with MS onset are for human herpesviruses, particularly Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6). Their role in MS clinical course is less clear, however. METHODS: Prospective cohort of 198 persons...
by PolygenicBlog on Sep 26, 2012

Herpesvirus active replication in multiple sclerosis: a genetic control?

Although the etiology of multiple sclerosis (MS) is unknown, it is generally believed that genetic, immunologic, and environmental factors are involved. The objectives of this study were: 1. to analyze if a genetic control could explain why HHV-6 wou...
by PolygenicBlog on Sep 1, 2012

Antiviral therapy of two patients with chromosomally-integrated human herpesvirus-6A presenting with cognitive dysfunction.

Human herpesvirus 6 (HHV-6) is a neurotropic virus implicated in central nervous system (CNS) dysfunction, multiple sclerosis, seizures and encephalitis. Inherited or "chromosomally integrated" HHV-6 (CIHHV-6) is a condition characterized by high...
by PolygenicBlog on Jul 11, 2012

Genetic Factors Influence Serological Measures of Common Infections

"Our results demonstrate, for the first time for many of these pathogens (Chlamydophila pneumoniae, Helicobacter pylori, Toxoplasma gondii, hepatitis A virus, influenza A and B, cytomegalovirus, Epstein-Barr virus, herpes simplex virus (HSV)-1 and...
by PolygenicBlog on Feb 18, 2012

Human herpesvirus-6 entry into the central nervous system through the olfactory pathway.

Image by AJC1 via Flickr Human herpesvirus-6 (HHV-6) is a neurotropic virus that has been associated with a wide variety of neurologic disorders, including encephalitis, mesial temporal lobe epilepsy, and multiple sclerosis. It appears to enter th...
by PolygenicBlog on Dec 31, 2011

Human herpesvirus 6 and 7 reactivation and disease activity in multiple sclerosis.

Multiple sclerosis pub-5799224524264318...
by PolygenicBlog on Dec 22, 2011

Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis.

 Multiple sclerosispub-5799224524264318...
by PolygenicBlog on Nov 29, 2011

Human herpesvirus-6 viral load and antibody titer in serum samples of patients with multiple sclerosis.

The results indicate that HHV-6 is implicated somehow in MS disease. Over time, rising HHV-6 IgG antibody titers together with an exacerbation and detection of HHV-6 DNA in serum samples of some MS patients suggests possible association between th...
by PolygenicBlog on Nov 10, 2011

IIntrathecal human herpesvirus 6 antibodies in multiple sclerosis and other demyelinating diseases presenting as oligoclonal bands inCSF

If it's not one virus it's another - in this case the ubiquitous HHV-6pub-5799224524264318...
by PolygenicBlog on Oct 18, 2011

Genetic Factors Influence Serological Measures of Common Infections.

The authors tested heritability for 13 common infections (Chlamydophila pneumoniae, Helicobacter pylori, Toxoplasma gondii, adenovirus 36 , hepatitis A virus, influenza A and B, cytomegalovirus, Epstein-Barr virus, herpes simplex virus (HSV)-1 and...
by PolygenicBlog on Oct 15, 2011
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