Hiv-1 Blog Posts

Human hepatitis B and immunodeficiency viruses integrate their retro-transcribed DNA proviruses into the human host genome. Existing antiretroviral drug regimens fail to directly target these intrachromosomal xenogenomes, leading to persist...

A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection. The system's two vital components are high levels of a molecule that becomes embedded in viral DNA like a code wri...

Pathogenic infection with simian immunodeficiency virus (SIV), a relative of HIV that infects non-human primates, is associated with increased diversity of gastrointestinal virus species in rhesus macaques, according to findings published today (Octo...

Oxford University scientists have discovered an adjuvant polymer (polyethyleneimine) that boosts the effect of vaccines against viruses like flu, HIV and herpes in mice. pub-5799224524264318...

Scientists at The Scripps Research Institute have discovered a surprisingly simple and safe method to disrupt specific genes within cells. The scientists highlighted the medical potential of the new technique by demonstrating its use as a safer al...

Upon HIV entry into target cells, viral cores are released and rearranged into reverse transcription complexes (RTCs), which support reverse transcription and also protect and transport viral cDNA to the site of integration. RTCs are composed of v...

Awakening the virus from its hiding place may allow its attack and elimination ...........pub-5799224524264318...

Two men with longstanding HIV infections no longer have detectable HIV in their blood cells following bone marrow transplants. The virus was easily detected in blood lymphocytes of both men prior to their transplants but became undetectable by ei...

A new study by scientists on the Florida campus of The Scripps Research Institute shows, in cell culture, a natural compound ( Cortistatin A) can virtually eliminate human immunodeficiency virus (HIV) in infected cells. The compound defines a nove...

STANFORD (US) — A new collection of compounds—derived from a tiny marine organism—activate hidden reservoirs of HIV that currently make AIDS nearly impossible to eradicate.pub-5799224524264318...

The Abstracts of the International Symposium on HIV & Emerging Infectious Diseases held May 23-25 in Marseilles, France are available online. They are published on www.retrovirology.com as individual articles and a PDF file of 54 pages. You c...

(Medical Xpress) -- An Australian research team has opened the door to understanding why certain drugs cause a so called altered immunity response when offered as treatment for certain specific ailments. In their paper published in the journal Nat...

Antibodies that help to stop the HIV virus have been found in breast milk. Researchers at Duke University Medical Center isolated the antibodies from immune cells called B cells in the breast milk of infected mothers in Malawi, and showed that the...

We examined the causes for decreased glutathione (GSH) in individuals with HIV infection. We observed lower levels of intracellular GSH in macrophages from individuals with HIV compared to healthy subjects. Further, the GSH composition found in ma...

Mount Sinai School of Medicine researchers have discovered that marijuana-like chemicals trigger receptors on human immune cells that can directly inhibit a type of human immunodeficiency virus (HIV) found in late-stage AIDS, according to new findi...

Stimulation of HIV-1-specific cytolytic T-lymphocytes facilitates elimination of latent viral reservoir after virus reactivation  From the Immunity Journal Highly active antiretroviral therapy (HAART) suppresses HIV-1 replication but cannot el...

Many psoriasis patients have the same gene variants as people who are not significantly affected by an HIV-1 infection. Charles Q. Choi reports pub-5799224524264318...

Image via Wikipedia Revelation of how certain compounds adhere so strongly to HIV’s coat points to a fresh therapeutic approach pub-5799224524264318...

Image via Wikipedia Clathrin mediated endocytosis is part of the machinery that recycles many surface receptors. The process is also hijacked by a  number of viruses. and usd as a route to enter the cell: A synthetic compound Pitstop 2, targe...

A protein found in semen makes HIV’s job of infecting immune cells easier, according to research published today in Cell Host & Microbe.These are semenogelin fragments forming amyloid fibrils that greatly enhance HIV infection. pub-57992245242...