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• Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer's Disease Using Metabolomics.
  on May 24, 2013 in metabolome Alzheimer's disease Biomarker
  Alzheimer's Disease (AD) currently affects more than 5 million Americans, with numbers expected to grow dramatically as the population ages. The pathophysiological changes in AD patients begin decades before the onset of dementia, highlighting the ur...
• Molecular Psychiatry - : The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
  on May 24, 2013 in Serotonin microbiome Neural development
  Bacterial colonisation of the intestine has a major role in the post-natal development and maturation of the immune and endocrine systems. These processes are key factors underpinning central nervous system (CNS) signalling. Regulation of the microbi...
• The TLR4 antagonist Eritoran protects mice from lethal influenza infection : Nature : Nature Publishing Group
  on May 24, 2013 in Toll-like receptor influenza
  There is a pressing need to develop alternatives to annual influenza vaccines and antiviral agents licensed for mitigating influenza infection. Previous studies reported that acute lung injury caused by chemical or microbial insults is secondary to t...
• BBC News - Feet home to more than 100 fungi
  on May 23, 2013 in Fungus microbiome
  We all have nearly 200 different types of fungi colonising our feet, scientists have discovered. Fungi live all over the human body, but their favourite spots are the heel, under toenails and between the toes, according to a US study. A new map of th...
• Negligible impact of rare autoimmune-locus coding-region variants on missing heritability : Nature : Nature Publishing Group
  on May 23, 2013 in Autoimmune disease GWAS
  Genome-wide association studies (GWAS) have identified common variants of modest-effect size at hundreds of loci for common autoimmune diseases; however, a substantial fraction of heritability remains unexplained, to which rare variants may contribut...
• Phthalates: Study links chemicals widely found in plastics, processed food to elevated blood pressure in children, teens
  on May 23, 2013 in Hypertension Phthalate Neurodevelopmental
   "Plastic additives known as phthalates are odorless, colorless and just about everywhere: They turn up in flooring, plastic cups, beach balls, plastic wrap, intravenous tubing and—according to the Centers for Disease Control and Prevention—...
• Addiction to unhealthy foods could help explain the global obesity epidemic
  on May 23, 2013 in Fructose childhood obesity
   "Research presented today shows that high-fructose corn syrup can cause behavioural reactions in rats similar to those produced by drugs of abuse such as cocaine. These results, presented by addiction expert Francesco Leri, Associate Professor...
• Futurity.org – Blood test could predict postpartum depression
  on May 22, 2013 in depression Biomarker
  pub-5799224524264318...
• B vitamins could delay dementia
  on May 22, 2013 in Vitamin B Dementia Alzheimer's disease
   "Despite spending billions of dollars on research and development, drug companies have been unable to come up with effective treatments for dementia and Alzheimer's Disease (AD). Now, A. David Smith at the University of Oxford and his colleague...
• Common food supplement fights degenerative brain disorders
  on May 22, 2013 in Neurodegeneration
  : "Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older people experiencing memory...
• Vitamin C Slays TB Bacteria | The Scientist Magazine®
  on May 22, 2013 in vitamin c tuberculosis
  "High doses of vitamin C can rapidly wipe out entire populations of drug-resistant strains of the bacteria that cause tuberculosis (TB) by inducing a chemical reaction that produces high levels of DNA-damaging oxidative radicals, according to a study...
• New immune system discovered
  on May 21, 2013 in bacteriophage Immune system
  "Taking previous research into consideration, we are able to propose the Bacteriophage Adherence to Mucus—or BAM—is a new model of immunity, which emphasizes the important role bacteriophage play in protecting the body from invading pathogens"...
• Type 1 Diabetes May Be Reversible With Immune Suppressor Protein
  on May 21, 2013 in immunosuppressant diabetes
  "A professor in Melbourne, Australia, who is on a mission to find a cure for type 1 diabetes, believes that the answer, or part of it, lies with an immune suppressor protein called CD52. And if it works for type 1 diabetes, then it may well work for...
• Early-life traffic-related air pollution exposure linked to hyperactivity
  on May 21, 2013 in Pollution ADHD
   "Early-life exposure to traffic-related air pollution was significantly associated with higher hyperactivity scores at age 7, according to new research from the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center."...
• Scientists Develop Drug That Improves Memory and Prevents Brain Damage in Mice
  on May 20, 2013 in Alzheimer's disease
  A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, improves memory and prevents brain damage in aged mice following short-term treatment. The findings, published May 14 in the journal Alzheimer's Research and...
• Good cholesterol linked to innate immunity: ASM
  on May 20, 2013 in cholesterol Innate immune system Host-pathogen
  Trypanosome Lytic Factor (TLF) has emerged as an arm of innate immunity, present only in humans and select non-human primates. TLF was originally discovered in human blood as a minor form of High-density lipoprotein (HDL), (good cholesterol), that ki...
• BBC News - Sunshine vitamin D 'may treat asthma'
  on May 20, 2013 in asthma Vitamin D
  The amount of time asthma patients spend soaking up the sun may have an impact on the illness, researchers have suggested. A team at King's College London said low levels of vitamin D, which is made by the body in sunlight, was linked to a worsening...
• Breathing Emission Particles Turns HDL Cholesterol From 'Good' To 'Bad'
  on May 19, 2013 in cholesterol Pollution
  MNT: Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein (HDL) cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.In addit...
• Ketamine shows significant therapeutic benefit in people with treatment-resistant depression
  on May 19, 2013 in depression Ketamine
   "Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the Icahn School of Med...
• Now we know why old scizophrenia medicine works on antibiotics-resistant bacteria
  on May 19, 2013 in phenothiazene Antibacterial
  Thioridazine is known to possess antibacterial effects, although it was not clear how this worked............ "When we treat the bacteria with antibiotics alone, nothing happens -- the bacteria are not even affected. But when we add both thioridazine...

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